# Best e-Prescribing Software 2026 | Capterra

> Find the top e-Prescribing software of 2026 on Capterra. Based on millions of verified user reviews - compare and filter for whats important to you to find the best tools for your needs.

Source: https://www.capterra.com/eprescribing-software

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# Best e-Prescribing Software

Last updated on April 24, 2026

How to find the right e-Prescribing Software?

Learn more from our team about e-Prescribing Software pricing features and benefits in our e-Prescribing Buyers Guide

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### 1\. What is e-Prescribing software?

[e-Prescribing software](https://www.capterra.com/eprescribing-software/) allows physicians and other healthcare providers to generate and send prescriptions electronically to pharmacies. The software helps avoid interpretation errors caused by handwritten prescriptions.

e-Prescribing software can be integrated with [Electronic Medical Records (EMR) or Electronic Health Records (EHR) systems](https://www.capterra.com/electronic-medical-records-software/) to bring the patient’s medical history to one platform. The software allows practitioners, such as you, to make decisions based on the patient’s previous medication dosage and make changes as required.

* * *

### 2\. The benefits of e-Prescribing software

-   **Easier data transmission:** With e-Prescribing software, medication information can move from a single source to doctors, pharmacies, hospital administrators, and insurance providers easily and quickly. You can check which medicines fall within a patient’s insurance and previous medication plan then prescribe to make medication affordable.
    
-   **Check prescription history:** You can get access to the patient’s medication history, including previous medication submission, discontinuation, allergies, as well as current medication. This prevents consequent risks to patients caused due to wrong medication and helps reduce medical errors.
    
-   **Access to regulatory compliance information:** There are various regulations for each country with which healthcare providers must comply. Some software tools provide regulatory information to providers so that they can access it before prescribing drugs, dosage, or frequency, especially in cases of controlled substances.
    

* * *

### 3\. Typical features of e-Prescribing software

-   **e-Prescribing:** Write and send electronic prescriptions to pharmacies from the point of care.
    
-   **Electronic Prescribing of Controlled Substances (EPCS) compliant:** Allows approved physicians to electronically prescribe controlled substances through an application certified as EPCS compliant.
    
-   **Formulary management:** Enables physicians, pharmacists, and other healthcare professionals to work together to provide better healthcare and minimize medical costs.
    
-   **Drug reference database:** Access a menu-driven drug database and check the drug-drug interaction based on the patient’s previous medication history and new ones that you aim to prescribe.
    
-   **Electronic prior authorization:** Enables real-time approval of specific medication that requires prior approval or a certificate from providers.
    
-   **Medication alerts/warnings:** Notifies providers of drug-drug interactions, and drug-allergy reactions before prescribing a medication.
    
-   **Medication history:** Features patients’ medication history to streamline medication reconciliation processes and ensure their safety.
    
-   **Mobile app:** Allows you to send prescriptions from your mobile device for quick transmission of information.
    
-   **Online refills:** Supports automated refills when approved by providers.
    
-   **Patient portal:** Follow up with patients regarding medication adherence and provide other healthcare tips.
    

* * *

### 4\. The cost of e-Prescribing software

Most products in the market are priced on a per user, per month basis and can be divided into three pricing tiers based on their starting price.

**Price ranges\*:**

-   $25 - $27
    
-   $28 - $181
    
-   $182+
    

_\*The pricing included is for the entry-level/lowest-priced offerings found on vendor websites as of October 1, 2021. These ranges correspond to the 25th, 75th, and 100th percentiles of pricing information gathered from vendor websites of sample products._

The above lists include pricing for the base plans of most products. Some e-Prescribing systems are integrated with EMR/EHR systems, therefore, the pricing can be higher than standalone e-Prescribing applications. An enterprise or premium product, which is priced higher, may include additional features such as real-time interactions, patient-specific formularies, comprehensive reporting, and surescript certifications.

* * *

### 5\. Considerations when purchasing e-Prescribing software

-   **Integrations:** e-Prescribing software is available as a standalone app or an integrated application that includes EMR/EHR software. If you don’t rely on an EMR/EHR framework (meaning that you don’t require previous medical history from other providers), then you can go for a standalone app. It is less expensive and works according to your business requirements. If you require the previous medical history of your patients and want to merge your healthcare IT solutions into one place, then it’s wise to go with an integrated app. If you go this route, you will get access to more data which will decrease the possibility of errors.
    
-   **User interface (UI) issues:** Software design issues such as problems with drop-down menus, automatic filing errors, and excess alerts can lead to incorrect medication submission. These errors can also impact workflow as pharmacists have to check with providers for clarifications. Therefore, choose a software tool that offers a user-friendly interface, and in turn, reduces manual errors.
    
-   **Pricing:** Integrated e-Prescribing tools can be expensive and often come with various additional costs. Apart from subscription fees, there can be maintenance and development costs involved. Some e-Prescribing applications come with transactional fees as well. Be sure to check for all hidden costs before deciding on a software solution.
    

* * *

### 6\. Relevant e-Prescribing software trends

-   **Cloud computing enhances patient care:** The rapid adoption of cloud computing in the healthcare industry has improved the quality of patient care. With cloud-based software, patients’ information from multiple sources can be found in one place known as a patient's chart. This makes the transmission of information from primary diagnosis to further care much faster. A quick and simplified process leads to better care. Cloud computing aims to enhance telehealth, medication adherence, and drug anti-theft. The use of this technology in e-Prescribing software can also protect patients’ personal information and also maintains the uniformity of medical records.
    
-   **Machine learning to reduce prescription errors:** [Machine learning](https://www.healthcareitnews.com/news/machine-learning-based-cds-can-accurately-intercept-rx-errors-study-finds) is used to decrease errors caused by manual typing and alert fatigue. This has been done using a rule-based expert system in which an expert creates several rules to apply to the input data. It is predicted that EHR systems will serve as the primary health IT interface point for healthcare providers. These systems leverage artificial intelligence and machine learning to decrease prescription and diagnostic errors using [speech-to-text technologies](https://www.netscribes.com/ai-in-ehr/).
    

* * *

**Sources**

Products evaluated for the pricing calculation were taken from [Capterra’s e-Prescribing software directory](https://www.capterra.com/eprescribing-software/). The pricing ranges exclude freemium versions of the products. The features highlighted were identified based on their relevance and the percentage of products in Capterra’s directory that offer them.

The following source was used for this document: 

1\. [Six Ways Cloud Computing is Improving Healthcare, Built In](https://builtin.com/cloud-computing/cloud-computing-in-healthcare) (Date accessed: October 1, 2021)

2\. [Machine learning-based CDS can accurately intercept Rx errors, study finds, Healthcare IT News](https://www.healthcareitnews.com/news/machine-learning-based-cds-can-accurately-intercept-rx-errors-study-finds) (Date accessed: October 1, 2021)

3\. [Four ways AI is revolutionizing EHR, Netscribes](https://www.netscribes.com/ai-in-ehr/) (Date accessed: October 1, 2021)

For more information consult our [e-Prescribing Buyers Guide](#buyers-guide-content)

[4.6 (29)](https://www.capterra.com/p/52615/ScriptSure/reviews/)

Award winning web-based electronic prescribing application for use by all provider specialties. Includes controlled prescribing (EPCS)! [Learn more about ScriptSure](https://www.capterra.com/p/52615/ScriptSure/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.9 (24)](https://www.capterra.com/p/111349/DxScript/reviews/)

DxScript/+EPCS is a HIPAA compliant, Surescripts and EPCS certified, cloud-based ePrescribing solution. [Learn more about DxScript](https://www.capterra.com/p/111349/DxScript/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.7 (142)](https://www.capterra.com/p/130289/MDToolbox-e-Prescribing/reviews/)

A certified e-prescribing system that can run stand-alone or integrate with EHR/PMs. [Learn more about MDToolbox-Rx](https://www.capterra.com/p/130289/MDToolbox-e-Prescribing/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

84% recommend this product

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[4.0 (40)](https://www.capterra.com/p/116370/PracticeSuite/reviews/)

Safely and securely transmit prescriptions, while maintaining regulatory compliance, with E-Prescribing from PracticeSuite. [Learn more about PracticeSuite](https://www.capterra.com/p/116370/PracticeSuite/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.3 (496)](https://www.capterra.com/p/110018/rxnt/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Safer, faster, EPCS-certified e-prescribing from anywhere with RXNT's industry-leading, intuitive, mobile E-Prescribing software. [Learn more about RXNT](https://www.capterra.com/p/110018/rxnt/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.2 (151)](https://www.capterra.com/p/120340/ChARM-EHR/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Cloud-based healthcare platform that helps businesses integrate EHR, practice management, telehealth, and patient engagement tools. [Learn more about CharmHealth](https://www.capterra.com/p/120340/ChARM-EHR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[3.9 (1362)](https://www.capterra.com/p/129169/Tebra/reviews/)

Tebra’s E-prescribing software simplifies prescriptions, reduces errors, and boosts patient safety with electronic submissions. [Learn more about Tebra](https://www.capterra.com/p/129169/Tebra/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.4 (34)](https://www.capterra.com/p/5409/HARMONY/reviews/)

Fully integrated HIPAA, ONC, compliant Practice Management software Scheduling, Portal, Insurance UB04 & 1500 & Patient billing. [Learn more about HARMONY Medical](https://www.capterra.com/p/5409/HARMONY/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.2 (102)](https://www.capterra.com/p/122222/Vitera-Intergy-EHR/reviews/)

Intergy is a cloud-based EHR and practice management platform that offers specialty-focused solution for ambulatory practices. [Learn more about Intergy](https://www.capterra.com/p/122222/Vitera-Intergy-EHR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## NextGen Office](https://www.capterra.com/p/31268/NextGen-Ambulatory-EHR/)

[4.0 (1280)](https://www.capterra.com/p/31268/NextGen-Ambulatory-EHR/reviews/)

NextGen Office is cloud-based EHR and practice management software aiding small practices in workflows, operations, and patient care. [Learn more about NextGen Office](https://www.capterra.com/p/31268/NextGen-Ambulatory-EHR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## TherapyNotes, LLC](https://www.capterra.com/p/118981/TherapyNotes-com/)

[4.7 (959)](https://www.capterra.com/p/118981/TherapyNotes-com/reviews/)

TherapyNotes is EHR and practice management software that helps behavioral health professionals streamline workflows and enhance care. [Learn more about TherapyNotes, LLC](https://www.capterra.com/p/118981/TherapyNotes-com/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

87% recommend this product

[## athenaOne](https://www.capterra.com/p/98735/athenaOne/)

[3.8 (909)](https://www.capterra.com/p/98735/athenaOne/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Web-based tool that offers electronic health records, revenue management & patient engagement modules for optimized patient outcomes. [Learn more about athenaOne](https://www.capterra.com/p/98735/athenaOne/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Pabau](https://www.capterra.com/p/140062/Pabau-CRM/)

[4.6 (617)](https://www.capterra.com/p/140062/Pabau-CRM/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Run your medical-led practice on one platform, from AI Scribe and ePrescribing to payments and growth tools. [Learn more about Pabau](https://www.capterra.com/p/140062/Pabau-CRM/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## DrChrono](https://www.capterra.com/p/89392/drchrono-Practice-Management/)

[3.9 (489)](https://www.capterra.com/p/89392/drchrono-Practice-Management/reviews/)

DrChrono eRx makes prescription writing a snap. Send e-prescriptions of regular & controlled substances anytime on iPad, iPhone or web. [Learn more about DrChrono](https://www.capterra.com/p/89392/drchrono-Practice-Management/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Practice Fusion](https://www.capterra.com/p/266915/Practice-Fusion/)

[3.7 (439)](https://www.capterra.com/p/266915/Practice-Fusion/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Practice Fusion is an intuitive EHR and billing software that helps medical practices streamline operations and improve patient care. [Learn more about Practice Fusion](https://www.capterra.com/p/266915/Practice-Fusion/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Qualifacts Insync](https://www.capterra.com/p/144484/InSync-EMR/)

[4.5 (391)](https://www.capterra.com/p/144484/InSync-EMR/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Prescribe online with InSync's EMR integrated eRx platform. Mobile friendly and directly connected to SureScripts for easy access. [Learn more about Qualifacts Insync](https://www.capterra.com/p/144484/InSync-EMR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Alleva](https://www.capterra.com/p/180899/Alleva/)

[4.5 (282)](https://www.capterra.com/p/180899/Alleva/reviews/)

Alleva is the most advanced EMR/EHR solution set built specifically for behavioral healthcare. It's an all-in-one easy-to-use platform. [Learn more about Alleva](https://www.capterra.com/p/180899/Alleva/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Covetrus vRxPro](https://www.capterra.com/p/204324/Covetrus-Prescription-Management/)

[4.3 (196)](https://www.capterra.com/p/204324/Covetrus-Prescription-Management/reviews/)

Covetrus® vRxPro® is the only complete business solution that actively helps you compete with online retailers. [Learn more about Covetrus vRxPro](https://www.capterra.com/p/204324/Covetrus-Prescription-Management/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Veradigm Practice Management](https://www.capterra.com/p/276109/Veradigm/)

[2.9 (139)](https://www.capterra.com/p/276109/Veradigm/reviews/)

Veradigm Practice Management is a cloud-based software that helps users manage scheduling, collections, claims and denials. [Learn more about Veradigm Practice Management](https://www.capterra.com/p/276109/Veradigm/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Teladoc Health](https://www.capterra.com/p/190055/Teladoc/)

[2.5 (90)](https://www.capterra.com/p/190055/Teladoc/reviews/)

Remote patient monitoring tool that allows medical professionals to provide virtual medical attention and prescriptions to patients. [Learn more about Teladoc Health](https://www.capterra.com/p/190055/Teladoc/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## epocrates](https://www.capterra.com/p/81890/Epocrates/)

[4.6 (88)](https://www.capterra.com/p/81890/Epocrates/reviews/)

Medical PDA software with drug interactions, dosing, pricing, adverse reaction, Medicare Part D, pharmacology, and safety monitoring. [Learn more about epocrates](https://www.capterra.com/p/81890/Epocrates/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## Provet](https://www.capterra.com/p/137569/Provet-Cloud/)

[4.1 (88)](https://www.capterra.com/p/137569/Provet-Cloud/reviews/)

Cloud veterinary software that runs your clinic from booking to invoice in one workspace — with 150+ integrations and built-in AI. [Learn more about Provet](https://www.capterra.com/p/137569/Provet-Cloud/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## OptiMantra](https://www.capterra.com/p/159365/OptiMantra/)

[4.8 (85)](https://www.capterra.com/p/159365/OptiMantra/reviews/)

Specialized EMR and practice management for individual and group integrative and wellness practices [Learn more about OptiMantra](https://www.capterra.com/p/159365/OptiMantra/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## 75health](https://www.capterra.com/p/140480/75health/)

[4.4 (78)](https://www.capterra.com/p/140480/75health/reviews/)

75health platform is easy to use and helps doctors, clinics, and hospitals to stay up-to-date. Streamlining the process to cloud-based [Learn more about 75health](https://www.capterra.com/p/140480/75health/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[## ChartLogic EHR](https://www.capterra.com/p/141875/ChartLogic/)

[3.9 (76)](https://www.capterra.com/p/141875/ChartLogic/reviews/)

Electronic medical records tool that helps businesses streamline workflows with custom templates, voice dictation & patient portal. [Learn more about ChartLogic EHR](https://www.capterra.com/p/141875/ChartLogic/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

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Table of Contents

-   [2\. The benefits of e-Prescribing software](#2-the-benefits-of-e-prescribing-software)
-   [3\. Typical features of e-Prescribing software](#3-typical-features-of-e-prescribing-software)
-   [4\. The cost of e-Prescribing software](#4-the-cost-of-e-prescribing-software)
-   [5\. Considerations when purchasing e-Prescribing software](#5-considerations-when-purchasing-e-prescribing-software)
-   [6\. Relevant e-Prescribing software trends](#6-relevant-e-prescribing-software-trends)

_Note: The applications referenced in this article are examples to show a feature in context and are not intended as endorsements or recommendations. They have been obtained from sources believed to be reliable at the time of publication._