# Best e-Prescribing Software for Small Businesses 2026 | Capterra

> Find and compare the 2026 best e-Prescribing software for small businesses, using our interactive tool to quickly narrow your choices based on businesses like yours.

Source: https://www.capterra.com/eprescribing-software/s/small-businesses

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# Best e-Prescribing Software for small-businesses

For more information consult our [e-Prescribing Buyers Guide](#buyers-guide-content)

[4.6 (29)](https://www.capterra.com/p/52615/ScriptSure/reviews/)

Award winning web-based electronic prescribing application for use by all provider specialties. Includes controlled prescribing (EPCS)! [Learn more about ScriptSure](https://www.capterra.com/p/52615/ScriptSure/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.9 (24)](https://www.capterra.com/p/111349/DxScript/reviews/)

DxScript/+EPCS is a HIPAA compliant, Surescripts and EPCS certified, cloud-based ePrescribing solution. [Learn more about DxScript](https://www.capterra.com/p/111349/DxScript/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.7 (142)](https://www.capterra.com/p/130289/MDToolbox-e-Prescribing/reviews/)

A certified e-prescribing system that can run stand-alone or integrate with EHR/PMs. [Learn more about MDToolbox-Rx](https://www.capterra.com/p/130289/MDToolbox-e-Prescribing/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

84% recommend this product

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[4.3 (498)](https://www.capterra.com/p/110018/rxnt/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Safer, faster, EPCS-certified e-prescribing from anywhere with RXNT's industry-leading, intuitive, mobile E-Prescribing software. [Learn more about RXNT](https://www.capterra.com/p/110018/rxnt/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.0 (40)](https://www.capterra.com/p/116370/PracticeSuite/reviews/)

Safely and securely transmit prescriptions, while maintaining regulatory compliance, with E-Prescribing from PracticeSuite. [Learn more about PracticeSuite](https://www.capterra.com/p/116370/PracticeSuite/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.2 (151)](https://www.capterra.com/p/120340/ChARM-EHR/reviews/)

[Capterra Shortlist](https://www.capterra.com/eprescribing-software/shortlist/)

Cloud-based healthcare platform that helps businesses integrate EHR, practice management, telehealth, and patient engagement tools. [Learn more about CharmHealth](https://www.capterra.com/p/120340/ChARM-EHR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[4.4 (34)](https://www.capterra.com/p/5409/HARMONY/reviews/)

Fully integrated HIPAA, ONC, compliant Practice Management software Scheduling, Portal, Insurance UB04 & 1500 & Patient billing. [Learn more about HARMONY Medical](https://www.capterra.com/p/5409/HARMONY/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

0.0 (0)

Netsmart OrderConnect is HIPAA-compliant solution and certified for Electronic Prescribing of Controlled Substances (EPCS). [Learn more about OrderConnect](https://www.capterra.com/p/241959/OrderConnect-e-Prescribing/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[3.9 (1364)](https://www.capterra.com/p/129169/Tebra/reviews/)

Tebra’s E-prescribing software simplifies prescriptions, reduces errors, and boosts patient safety with electronic submissions. [Learn more about Tebra](https://www.capterra.com/p/129169/Tebra/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

[3.8 (34)](https://www.capterra.com/p/86870/CarePaths-EHR/reviews/)

HIPAA-Compliant & ONC-Certified Cloud-Based EHR & Practice Management with Free Telehealth, Claims, and Eligibility. [Learn more about CarePaths EHR](https://www.capterra.com/p/86870/CarePaths-EHR/)

e-Prescribing features reviewers most value

Customizable Templates

Drug Reference Database

EPCS Compliant

Formulary Management

Medication Alerts/Warnings

Medication History

Multi-Location

Prescription Renewal

Records Management

## Top-rated software of 2026

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