--- title: "RealTime-CTMS Software Pricing, Alternatives & More 2026 | Capterra" description: "With the help of Capterra, learn about RealTime-CTMS Software - reviews, pricing plans, popular comparisons to other Clinical Trial Management products and more." source_url: "https://www.capterra.com/p/126679/RealTime-CTMS/" page_type: "product" language: "en" --- # RealTime-CTMS Software Review 2026: Features, Integrations, Pros & Cons Last updated on August 26, 2026 Provider data verified by our Software Research team, and reviews moderated by our Reviews Verification team. [Description](#description)[Use cases](#use-cases)[Alternatives](#alternatives)[FAQs](#faqs)[Features](#features)[Pricing](#pricing)[Integrations](#integrations)[Support](#support)[Reviews](#reviews) RealTime-CTMS ## What is RealTime-CTMS? RealTime CTMS is an enterprise-grade clinical trial management system that gives teams real-time visibility into enrollment and trial progress across all studies. Designed from real site experience, the platform scales with your organization and includes powerful financial reporting to manage both the operational and business sides of research. As part of the RealTime eClinical platform, CTMS integrates natively with eSource and eReg for centralized oversight across the full trial lifecycle. A trusted, proven solution shaped by the teams who use it every day. ## What is RealTime-CTMS used for? [Clinical Trial Management](https://www.capterra.com/clinical-trial-management-software/)[Patient Engagement](https://www.capterra.com/patient-engagement-software/)[Document Management](https://www.capterra.com/document-management-software/) Overall rating Based on 68 user reviews Reviews sentiment Positive 100% Neutral 0% Negative 0% Starting price $500 Other, Per Month Free trial not available Capterra Shortlist charts the highest-rated and most popular products... Our "Best of" badge program showcases products with the highest ratings... Our "Best of" badge program showcases products with the highest ratings... ## RealTime-CTMS alternatives Highest Rated [4.9 (21)](https://www.capterra.com/p/133931/ClinCapture/reviews/) Starting price $2000.00 Per User, Per Month Pricing Options Free Trial Free Version User Rating 100% of reviewers rated it above 4 stars [4.7 (204)](https://www.capterra.com/p/143532/Castor-EDC/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 98% of reviewers rated it above 4 stars [4.7 (2,922)](https://www.capterra.com/p/158456/JotForm-4-0/reviews/) Starting price $39.00 Per User, Per Month Pricing Options Free Trial Free Version User Rating 96% of reviewers rated it above 4 stars [4.5 (144)](https://www.capterra.com/p/161845/Square-9/reviews/) Starting price $68.00 Per User, Per Month Pricing Options Free Trial Free Version User Rating 93% of reviewers rated it above 4 stars [View all alternatives](https://www.capterra.com/p/126679/RealTime-CTMS/alternatives/) ## FAQs about RealTime-CTMS Overview ### What problems does RealTime-CTMS solve? RealTime-CTMS helps research sites solve fragmented clinical trial workflows, manual referral entry, disconnected patient communications, and burdensome document, payment, and study tracking. Study coordinators, regulatory staff, research administrators, and clinic operations teams benefit most by centralizing recruitment, eSource, eDocs, invoicing, stipend payments, reporting, and fast issue resolution. Answer based on 22 reviews Overview ### Which roles and teams benefit most from RealTime-CTMS? RealTime-CTMS is most used by clinical research coordinators, research managers, and site directors who oversee study workflows, regulatory tasks, and participant tracking. Operations and administrative leaders use it to streamline site management and reporting, while executives rely on its visibility to monitor performance, compliance, and business efficiency across research programs. Answer based on 62 reviews Overview ### What company size and industries is RealTime-CTMS built for? RealTime-CTMS is built mainly for small research organizations, with 89% of reviewers from small businesses and 61% in Research. It also serves hospital-based research systems and larger groups such as sponsors, CROs, multi-site networks, and academic medical centers, with 18% in Hospital & Health Care and 10% in Pharmaceuticals for clinical trial management. Answer based on 66 reviews Features and Usability ### What are the key features of RealTime-CTMS? RealTime-CTMS includes core clinical trial management features such as patient recruiting, visit scheduling, patient appointment reminders, reporting, and financial tracking with invoicing and subject payments. Differentiating capabilities include eRegulatory document management, electronic data capture, text messaging, and study progress tracking, all supported by role-based permissions and audit trails. Answer based on 22 reviews Overview ### How well does RealTime-CTMS handle clinical trial management? RealTime-CTMS handles end-to-end clinical trial management in one system for many research sites and study teams. It supports patient tracking, recruitment, scheduling, regulatory documents, billing, stipends, and remote document access. Many teams find the workflow intuitive, though some note newer eSource capabilities still need ongoing development. Answer based on 16 reviews Integrations ### Which third-party tools and platforms does RealTime-CTMS integrate with? RealTime-CTMS integrates with 3 third-party tools: Mailchimp, Microsoft Outlook, and Twilio. The catalog lists communication and email connections for outreach and messaging workflows. Answer based on 9 reviews Getting Started and Support ### How easy is it to onboard and train a team on RealTime-CTMS? RealTime-CTMS is generally easy to onboard for coordinators and day-to-day users, with in-person training, live online sessions, webinars, videos, and documentation available. Reviewers say recorded, site-specific training and the University video library help new staff ramp up quickly, while admins and teams adopting eSource or deeper features may need more hands-on time. Answer based on 17 reviews Getting Started and Support ### What customer support options does RealTime-CTMS offer, and how do users rate the experience? RealTime-CTMS offers email/help desk, FAQ/forum, knowledge base, phone support, and chat. Users generally describe support as fast, accessible, knowledgeable, and willing to address issues or requested changes quickly. Training and onboarding are viewed as thorough, and teams say feedback is heard, though some note a learning curve. Answer based on 22 reviews Features and Usability ### Is RealTime-CTMS easy to use? RealTime-CTMS feels easy to learn and navigate for many clinical research teams, including multi-site operations and CRO users. It offers clear workflows, simple training, recorded onboarding sessions, and accessible support. Most users describe low frustration during adoption, though a few mention minor gaps for non-US sites or invoice editing. Answer based on 15 reviews ## Features AI summary Based on 349 Clinical Trial Management reviews Capterra reviewers point to these as the top priorities when choosing Clinical Trial Management software: - **21 CFR Part 11 Compliance** (**72%** of reviewers rated this feature as critical) - **Audit Trail** (**52%**) - **HIPAA Compliant** (**76%**) RealTime-CTMS supports all three features buyers rate most highly: **21 CFR Part 11 Compliance**, **Audit Trail**, and **HIPAA Compliant**. Together, these capabilities help organizations maintain regulatory compliance, track system and data changes clearly, and protect sensitive patient information, allowing teams to manage clinical trials with stronger oversight and confidence. 21 CFR Part 11 Compliance 4.8 (6) 66.67% of 6 reviewers that rated this feature as important or highly important Shows that electronic documents are authentic and linked to specific records Audit Trail 4.7 (3) 66.67% of 3 reviewers that rated this feature as important or highly important A record of all activities within the system, including user access, changes made, etc. HIPAA Compliant 4.9 (7) 71.43% of 7 reviewers that rated this feature as important or highly important Compliant with HIPAA, which sets standards for sensitive patient data protection Electronic Data Capture 4.8 (5) 40.00% of 5 reviewers that rated this feature as important or highly important Import, collect, and capture data from multiple sources Clinical Study Management 4.8 (11) 54.55% of 11 reviewers that rated this feature as important or highly important Tools to manage single or multiple clinical studies within a centralized platform Financial Management 4.9 (8) 37.50% of 8 reviewers that rated this feature as important or highly important Plan, manage, and track the financial activities of an individual or organization RealTime-CTMS 50 features ### All Features - 21 CFR Part 11 Compliance: Shows that electronic documents are authentic and linked to specific records - Access Controls/Permissions: Define levels of authorization for access to specific files or systems - Activity Dashboard: Dashboard to view the status of ongoing processes, identify current incidents and track past activities - Activity Tracking: Track and document all activities across devices, networks, and other systems - Ad hoc Reporting: Generate one-off reports that meet information requirements - Alerts/Notifications: Alerts or notifications of various types such as pop-up messages, sounds, banners, or badges - API: Application programming interface that allows for integration with other systems/databases - Audit Trail: A record of all activities within the system, including user access, changes made, etc. - Automated Scheduling: Automatically create schedules based on business needs or employee availability and qualifications - Calendar Management: Track and manage schedules and meetings via an integrated calendar - Clinical Study Management: Tools to manage single or multiple clinical studies within a centralized platform - Compliance Management: Track and manage adherence to policies for any service, product, process, or supplier - Customizable Forms: Customize contracts and forms to collect specific information - Customizable Reports: Alter the layout and content of reports - Data Capture and Transfer: Import, collect, and capture data from multiple sources - Data Import/Export: Import and export data to and from software applications - Data Storage Management: Manage and store data in a database - Data Verification: Process of checking different types of data for accuracy to avoid errors or inconsistencies - Data Visualization: Graphical representation of data - Digital Signature: Electronic signing method that validates the authenticity and integrity of a digital document - Document Capture: Scan, move or upload electronic files within the software's repository - Document Management: Store, manage, and track all electronic documents in a centralized location - Document Storage: Store and organize documents in a centralized system - Drag & Drop: Assemble applications and processes by dragging over and arranging pre-built components - Electronic Data Capture: Import, collect, and capture data from multiple sources - EMR/EHR: Create and securely store digital patient records - Enrollments/Onboarding: Manage the enrollment and onboarding of all new members and accepted applications - Financial Management: Plan, manage, and track the financial activities of an individual or organization - Forms Management: Store, manage and track all forms in a centralized location - Full Text Search: Search for specific words or phrases within a document or database - HIPAA Compliant: Compliant with HIPAA, which sets standards for sensitive patient data protection - Messaging: Communicate using messages within the system - Monitoring: Observe and track the demand, usage, progress or quality of a system, product, or user - Patient Engagement: Allows medical providers to engage patients in a variety of ways to ensure their health. - Patient Management: Managing and tracking patient health, progress, communication, and treatment plans - Patient Monitoring: Observing and tracking a patient's health status, condition, and wellbeing - Patient Recruiting: Helps clinical trials/labs get patients for participation. - Progress Tracking: Reporting on how each user, task or process has advanced since its initiation - Randomization: Randomize the displayed order of questions and answer options - Real-Time Data: Receive data and information in real time - Real-Time Monitoring: Active monitoring of systems, applications, or networks - Real-Time Reporting: Active reporting of data and metrics - Reminders: Timed notification for any upcoming task, deadline, appointment, or activity - Reporting & Statistics: Collection, analysis, and representation of numerical data and generation of reports to understand various patterns - Role-Based Permissions: Set & manage permission levels based on user roles and restrict access to only authorized individuals - Scheduling: Plan availability and assign specific time slots for tasks and resources - Third-Party Integrations: Set up connections to third-party platforms to improve business processes - Trial Design: Allows clinics and academic institutions to create trials and studies from scratch. - User Management: Manage user accounts, profiles, roles, permissions, and other details across applications, devices or networks - Workflow Management: Create, design and manage workflows for repetitive tasks --- Get Advice We can help you find the software with the features you need. Features 4.7 (68) 4.7 Based on 68 reviews ## Pricing Value for money 4.9 (60) Basic $500.00 Other,Per Month Value for money 4.9 (60) 4.9 Based on 60 reviews ## Integrations [ Microsoft Outlook](https://www.capterra.com/p/227138/Microsoft-Outlook/)[ Twilio](https://www.capterra.com/p/180158/Twilio-Communications-Platform/) Connect with a Capterra advisor for a free 15-minute consultation Get a personalized software list aligned to your business needs with guidance from our expert advisors. Our team has helped 1 million+ businesses like yours find options that fit their needs. ## Support, customer service and training options Customer Service 4.9 (66) Support - Email/Help Desk - FAQs/Forum - Knowledge Base - Phone Support - 24/7 (Live rep) - Chat Training - In Person - Live Online - Webinars - Documentation - Videos Deployment - Web - Android - iPhone/iPad Typical users - Freelancers - Small businesses - Mid size businesses - Enterprises Customer Service 4.9 (66) 4.9 Based on 66 reviews ## User reviews Overall rating 4.9 Based on 68 reviews Filter by rating 5(58) 4(10) 3(0) 2(0) 1(0) Mentioned topic Sorted by most recent LH Leslie H. Founder Financial Services ### "This CTMS covers all the bases, gives you solid tracking capabilities, and won't take forever to get the hang of." 4.0 Overall Rating 4.0 4.0 Ease of Use 5.0 5.0 Features 4.0 4.0 Customer Service 4.0 4.0 Likelihood to Recommend 8/10 August 21, 2026 Honestly, my experience with RealTime-CTMS has been pretty good overall. It gives you one central place to manage recruitment, participant visits, study activities, financials, and reporting — which means we're not juggling a dozen spreadsheets anymore. It's much easier to get a quick sense of where each study stands. For day-to-day stuff, it's pretty intuitive. Scheduling visits, pulling up participant info, tracking recruitment — those all work smoothly. That said, the more advanced stuff like setting up a new study, digging into accounting reports, managing permissions, or handling integrations definitely takes some extra training. Once you've got everything configured the way you want, it does end up saving a lot of administrative time. Feature-wise, this platform has a lot going for it, especially for a research site. The appointment reminders, visit tracking, automatic target-date calculations, recruitment tools, financial reports, and document storage are all genuinely useful. I also like that you can attach files directly to a study and share them easily. But keep in mind, it's not really built to be a general file-management tool — that's just not its main strength. Exporting and file conversion work fine for standard reports and day-to-day operational data. But if you need something for an external presentation, be prepared to do some manual formatting afterward. More flexibility with report layouts and export options would definitely be a nice upgrade. Customer support has been decent for routine questions — they're responsive and helpful. But when you get into trickier configuration problems or financial glitches, you might need to go back and forth a bit. I've also hit a few bugs here and there, though nothing that's ever stopped me from using the system for long. For a busy research site that uses the recruitment, scheduling, financial, and reporting features daily, the cost is pretty reasonable. But if you're a smaller organization with only a handful of studies, the price tag and the time it takes to set everything up might be a tougher sell. All in all, RealTime-CTMS is a solid, comprehensive system. It just has a learning curve, occasional quirks, and some reporting limitations that keep it from being perfect. Pros RealTime-CTMS has made a real difference in how we run clinical research. It pulls together all the key pieces — enrolling participants, scheduling visits, keeping track of studies, sending appointment reminders, and managing the financial side of things. The calendar with automatic visit-window calculations is a big help for staying on top of deadlines, and it's definitely reduced scheduling errors. I also appreciate the recruitment tracking feature, which gives a clear view of where prospective participants are in screening. But what I value most is how it links operational and financial data, giving the team real insight into study performance. Cons There’s no shortage of features here, but that definitely comes with a learning curve when you're just getting started. Some screens feel a bit cluttered, and a few workflows take more clicks than you'd expect. Getting studies, financial rules, reports, and user permissions configured requires time and careful attention. I've also run into the occasional bug or hiccup—mostly with loading times, notifications, and data refreshing. The reports and exported files are useful, though the layout and customization options could be a lot more flexible. And for smaller research sites, the price tag might be tough to justify. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. RC Ricardo C. VP, Operations Pharmaceuticals ### "Great Value and Functionality, Hoping Support Bounces Back" 4.0 Overall Rating 4.0 4.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 4.0 4.0 Likelihood to Recommend 9/10 August 20, 2026 My personal experience with RealTime-CTMS since 2017 has been overwhelmingly positive. The platform offers a complete, user-friendly, and cost-effective solution built specifically around the daily operational and financial needs of a clinical research site. While we have encountered a temporary increase in system bugs and slower support ticket resolution times in recent months, upper management stepped in to help address our critical issues, and we have been informed that structural changes are currently being made to improve support responsiveness. Overall, we view these recent challenges as short-term growing pains, and we remain confident in our continued partnership with RealTime given their strong track record and robust system capabilities. Pros RealTime-CTMS is an exceptionally user-friendly platform clearly built from the clinical research site perspective. Having used the system since 2017, I consider it a great value for the money, offering a robust feature set that easily rivals any major competitor in the industry. It comprehensively covers all operational and financial aspects of running a site through its various integrated modules. The platform excels at managing recruitment efforts and tracking enrollment via its CRM capabilities, streamlines study visit logistics through intuitive study templates and clear visit tracking, and provides seamless electronic source data capture through eSOURCE along with clean Investigator Site File organization in eDOCS. Overall, it delivers a complete, site-centric solution that effectively powers daily operations and financial management. Cons Recently, our team has experienced an increase in system bugs alongside a decline in support responsiveness, with open tickets taking much longer to resolve than in the past. Critical issues, such as inaccurate financial report data and an ongoing inability to merge duplicate subject profiles, remained open for weeks, with the duplicate profile issue still unresolved. While direct phone support was previously easy to access, resolving recent issues required escalation through upper management. That said, company leadership has communicated that structural changes are underway to address support timeliness, so these recent setbacks appear to be growing pains rather than a permanent shift. Alternatives considered [CRIO](https://www.capterra.com/p/166083/Clinical-Research-IO/) Reasons for choosing RealTime-CTMS We had a less than ideal experience with CRIO during a study where the sponsor provided the access. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. DT Diana T. Clinical Office Manager Medical Practice ### "RealTim-CTMS Review " 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 4.0 4.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 May 8, 2026 My experience with RealTime-CTMS is that the information is real time and is available to you quickly on a real time basis, very helpful when is dealing with patient care on a day to day basis. Pros We like to use RealTime CTMS to view patient records and images for patients interventions and surgical options. Cons Sometimes the Images don't load, records are not not readable but over all this is just a small issue. That can be overcome. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. MP Maria Paula Z. Finance Assistance Research ### "RealTime-CTMS Review" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 April 12, 2024 Pros Real Time-CTMS offers a set of features that help clinical trial management. I also love the training program that covers every user's needs, and the customer service deserves a 5-star rating! Cons I wish there could be a way to import study visits. It would be such a time saver and minimize the risk of errors during data entry. Switched from [CRIO](https://www.capterra.com/p/166083/Clinical-Research-IO/) Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. RA Ravi A. Director of Clinical Administration Research ### "RealTime CTMS Review: Seamlessly Serving Clinical Trial Needs" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 October 19, 2023 1\. RealTime has likely helped streamline various aspects of your clinical trial management. 2. The accuracy and regulatory compliance offered by RealTime CTMS are paramount in clinical research.3. Company's commitment to continuous improvement. Pros RealTime CTMS is a standout Clinical Trial Management System known for its user-friendliness and exceptional customer support. It excels in document management (eDocs), data capture (eSource), and patient management (CTMS). With a user-friendly interface and a commitment to customer satisfaction, it's a top choice for clinical research professionals seeking efficiency and ease of use. Cons I don't have many criticisms to offer about RealTime CTMS. If I were to suggest an area for improvement, it would be to focus on enhancing the Enterprise system and the Finance module. Alternatives considered [CRIO](https://www.capterra.com/p/166083/Clinical-Research-IO/) Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. TD Tim D. Manager Research ### "Real Time" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 April 29, 2023 I thoroughly enjoy the software. It’s very helpful for our CRO Pros I enjoy the university. It’s great to always have that resources readily available Cons It’s so in-depth that it can seem daunting at times Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. LM Luis M. Clinical Research Supervisor Research ### "RealTime will elevate your clinical trials department" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 November 30, 2022 Pros Virtually everything. The UI is clean and intuitive. Branded options for the site and Pay cards are a nice touch. Accounting functions such as invoicing/payment tracking and the template building services have been game changers. All you need is in one place and it’s easy to understand thanks to the thorough trainings. Also, can’t say enough good things about the staff/customer service. RealTime has truly elevated our clinical trials department and helped us to grow as rapidly as we have! Cons Very minor and not truly a dislike: RT app doesn’t have accounting capabilities. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. MW Melonie W. Research Data Manager Research ### "There's a learning curve, but they're supportive." 4.0 Overall Rating 4.0 4.0 Ease of Use 3.0 3.0 Features 4.0 4.0 Customer Service 4.0 4.0 Likelihood to Recommend 7/10 January 4, 2022 Pros This software really is quite fully featured, and the things that it does lack are likely in the development pipeline for future releases (as long as you let the support staff know!). Cons It is HARD to navigate this software. It is NOT intuitive (and I'm a digital native). The labeling of different sections seems rather obtuse (and I think, for example, it's strange to track user accounts for external providers/visiting Monitors in a completely separate location from user accounts for site staff - shouldn't all user accounts be in one place?). Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. CB Carmen B. Director of Research Services Research ### "eSource/eReg and so much more!" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 December 20, 2021 Pros We were looking for an electronic software program for our source and regulatory and decided on RealTime after our initial demo and meeting. It is obvious on all levels that the product has been designed by people that have worked in the clinical trial arena! We are just over a year into using RT and it has exceeded our needs. While the eSource side is less mature than the eReg it continues to develop and customer service readily takes suggestions with most ideas already on their roadmap. We continue to learn what it has to offer and have just begun looking into the text options. We also are interested in switching our CTMS in the future. I can not say enough about their support team, 5 stars all the way around! Cons The only thing I could mention is the learning curve upfront, but this would be with any new product and its implementation. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. DH Danielle H. Financial Director Research ### "Excellent Customer Service" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 December 20, 2021 I enjoy working with this system. There are some features that go unused or under-utilized, but hopefully my employer will upgrade that in the future. Pros This software was easy to learn with informative instructional training videos. If I have a question or suggestion, customer service always responds timely and makes me feel important. Cons I'd like the reports to be more personalized. I look forward to that possibility in the future. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. [View all Reviews](https://www.capterra.com/p/126679/RealTime-CTMS/reviews/) ## Top-rated software of 2026 ### Fill out the form and we'll send a list of the top-rated software based on real user reviews directly to your inbox. Popular comparisons [Jotform vs RealTime-CTMS](https://www.capterra.com/compare/126679-158456/RealTime-CTMS-vs-JotForm-4-0)