# Florence eTMF Software Pricing, Alternatives & More 2026 | Capterra > With the help of Capterra, learn about Florence eTMF Software - reviews, pricing plans, popular comparisons to other Clinical Trial Management products and more. Source: https://www.capterra.com/p/276610/Florence-eTMF --- # Florence eTMF Software Review 2026: Features, Integrations, Pros & Cons Last updated on March 13, 2026 Provider data verified by our Software Research team, and reviews moderated by our Reviews Verification team. Independent research methodology Capterra’s researchers use a mix of verified reviews, independent research and objective methodologies to bring you selection and ranking information you can trust. While we may earn a referral fee when you visit a provider through our links or speak to an advisor, this has no influence on our research or methodology. [Learn more](https://www.capterra.com/resources/proprietary-data-research/) How Capterra verifies reviews Capterra carefully verified over 2.5 million+ reviews to bring you authentic software experiences from real users. Our human moderators verify that reviewers are real people and that reviews are authentic. They use leading tech to analyze text quality and to detect plagiarism and generative AI. [Learn more](https://www.capterra.com/resources/how-we-verify-reviews/) How Capterra ensures transparency Capterra lists all providers across its website—not just those that pay us—so that users can make informed purchase decisions. Capterra is free for users. Software providers pay us for sponsored profiles to receive web traffic and sales opportunities. Sponsored profiles include a link-out icon that takes users to the provider’s website. [Learn more](https://www.capterra.com/resources/how-we-ensure-transparency/) [Description](#description)[Use cases](#use-cases)[Alternatives](#alternatives)[Features](#features)[Pricing](#pricing)[Support](#support)[Reviews](#reviews) Florence eTMF ## What is Florence eTMF? Florence Electronic trial master file (eTMF) is the only eTMF that combines ease of use with integrated remote access to study sites on the Florence platform. Implementing an eTMF is critical for Sponsors and CROs that want to increase study capacity, and enable more trials. With over 10,000 research sites connected to the Florence Network, we have an intimate understanding of the research site and the site’s eISF where over 80% of a TMF’s documents originate. ## What is Florence eTMF used for? [Clinical Trial Management](https://www.capterra.com/clinical-trial-management-software/) Overall rating Based on 18 user reviews Reviews sentiment Positive \- Neutral \- Negative \- Starting price Free trial not available Capterra Shortlist charts the highest-rated and most popular products... Our "Best of" badge program showcases products with the highest ratings... Our "Best of" badge program showcases products with the highest ratings... ## Florence eTMF alternatives Highest Rated [4.8 (44)](https://www.capterra.com/p/253399/ShareCRF/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 100% of reviewers rated it above 4 stars [4.5 (83)](https://www.capterra.com/p/200364/Florence-eBinders/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 95% of reviewers rated it above 4 stars [4.7 (204)](https://www.capterra.com/p/143532/Castor-EDC/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 98% of reviewers rated it above 4 stars [4.8 (6)](https://www.capterra.com/p/275503/SiteLink/#reviews) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 100% of reviewers rated it above 4 stars [View all alternatives](https://www.capterra.com/p/276610/Florence-eTMF/alternatives/) ## Features Features with the highest number of reviews are displayed first. Those that have no reviews appear next, sorted alphabetically. 21 CFR Part 11 Compliance 4.7 (15) 100.00% of 15 reviewers that rated this feature as important or highly important Shows that electronic documents are authentic and linked to specific records Audit Trail 4.8 (13) 107.69% of 13 reviewers that rated this feature as important or highly important A record of all activities within the system, including user access, changes made, etc. Clinical Study Management 4.5 (13) 100.00% of 13 reviewers that rated this feature as important or highly important Tools to manage single or multiple clinical studies within a centralized platform Document Management 4.4 (13) 115.38% of 13 reviewers that rated this feature as important or highly important Store, manage, and track all electronic documents in a centralized location HIPAA Compliant 4.8 (12) 116.67% of 12 reviewers that rated this feature as important or highly important Compliant with HIPAA, which sets standards for sensitive patient data protection Workflow Management 4.4 (12) 116.67% of 12 reviewers that rated this feature as important or highly important Create, design and manage workflows for repetitive tasks Florence eTMF 25 features Shows that electronic documents are authentic and linked to specific records Define levels of authorization for access to specific files or systems Dashboard to view the status of ongoing processes, identify current incidents and track past activities Track and document all activities across devices, networks, and other systems Alerts or notifications of various types such as pop-up messages, sounds, banners, or badges Plan, schedule, and execute organization's accounts and assets to ensure compliance with policies and laws A record of all activities within the system, including user access, changes made, etc. Tools to manage single or multiple clinical studies within a centralized platform Customize contracts and forms to collect specific information Import, collect, and capture data from multiple sources Import and export data to and from software applications Electronic signing method that validates the authenticity and integrity of a digital document Store, manage, and track all electronic documents in a centralized location Store and organize documents in a centralized system Assemble applications and processes by dragging over and arranging pre-built components Compliant with HIPAA, which sets standards for sensitive patient data protection Observe and track the demand, usage, progress or quality of a system, product, or user Reporting on how each user, task or process has advanced since its initiation Active monitoring of systems, applications, or networks Timed notification for any upcoming task, deadline, appointment, or activity Collection, analysis, and representation of numerical data and generation of reports to understand various patterns Set & manage permission levels based on user roles and restrict access to only authorized individuals Set up connections to third-party platforms to improve business processes Manage user accounts, profiles, roles, permissions, and other details across applications, devices or networks Create, design and manage workflows for repetitive tasks Features 4.2 (18) 4.2 Based on 18 reviews ## Pricing Value for money 4.5 (10) ### Starting price Free trial not available Value for money 4.5 (10) 4.5 Based on 10 reviews ## Support, customer service and training options Customer Service 4.8 (12) Support - Email/Help Desk - FAQs/Forum - Knowledge Base - Phone Support - 24/7 (Live rep) - Chat Training - In Person - Live Online - Webinars - Documentation - Videos Deployment - Web - Android - iPhone/iPad Typical users - Freelancers - Small businesses - Mid size businesses - Enterprises Customer Service 4.8 (12) 4.8 Based on 12 reviews ## User reviews Overall rating 4.6 Based on 18 reviews Filter by rating 5(10) 4(8) 3(0) 2(0) 1(0) Mentioned topic Sorted by most recent AU Anonymous User Lead CRA Biotechnology ### "Florence review" 5.0 Overall Rating 5.0 5.0 Ease of Use 4.0 4.0 Features 4.0 4.0 Customer Service 5.0 5.0 Likelihood to Recommend 9/10 February 21, 2023 paper TMF is a difficult endeavor - this cuts study start in half, and allows for consistent and ongoing visibility into the files so you can keep on top of things. Pros The fact that documents are electronic, easily located and retrievableeasy to share with study sites, easy to collect documents and to QC Cons the reporting features are only worthwhile if everyone including your ISF sites use tags and labels staff training and implementation at the sponsor has been uneven so it is of little value.the search function could use some real updating. lets make it folder specific! Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. TO Taylor O. Clinical Trial Project Manager Research ### "Great Potential" 4.0 Overall Rating 4.0 4.0 Ease of Use 2.0 2.0 Features 2.0 2.0 Customer Service 0.0 0.0 Likelihood to Recommend 5/10 February 16, 2023 Pros The email documents to the binder feature is a huge positive. Granting user access it also simple, and the ability to create digital template logs is beneficial. Also, the ability to change the title of a document if there is an error is a huge plus. I've worked in other eTMFs and to change a document name you have to make it "obsolete" and go through tons of other processes to correct it. Cons There is no search function. You cannot search for a specific document if you do not know which folder it is stored in. The binder structure for my studies is complicated, so I sometimes spend 10 minutes trying to decipher where a colleague or site might have saved a specific document. Also, when moving a document, you need to select all the folders to put it in which can be a bit time consuming. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. SG Stephen G. Regulatory Documents Project Manager and IRB Liaison Research ### "Florence eTMF Review\_16FEB2023\_SG" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 February 16, 2023 Very satisfied overall. Pros Signature requests are very easy to assign and follow-up on. Cons Moving documents could be easier. Having to drill down through every folder is cumbersome. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. AF Anke F. Clinical Trials Manager Medical Devices ### "Perscpectinve form a Clinical Trials Manager (Sponsor site) using site's Florence ebinder" 4.0 Overall Rating 4.0 4.0 Ease of Use 4.0 4.0 Features 4.0 4.0 Customer Service 0.0 0.0 Likelihood to Recommend 5/10 February 15, 2023 It is great to have a shared platform with the site. Pros I like that I have access to the site's reg binder and don't need to bother them about essential documents. I like that they can send me notifications Cons I wished I could set up an alert for myself that emails me whenever a document is uploaded or changed. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. ST Sara Tisj M. Director Clinical Affairs Medical Devices ### "Ease of Use and Compliance " 4.0 Overall Rating 4.0 4.0 Ease of Use 4.0 4.0 Features 3.0 3.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 February 15, 2023 Overall, Florence onboarding and customer service is amazing. They go above and beyond and are always supportive. Although pricing is more than average and there is some downsides overall the experience is great. Pros Florence has the ability to implement a regulatory compliant trial management file system easily for both you and all your clinical sites. Implementing changes within your file structure is easy. Uploading documents and adding users are easy to complete with simple toggles of buttons and drag and drops. Cons Florence still has some challenges in terms of bulk file uploading for example when a new site is onboarded and was previously on paper or transferred. Also, there is no interface to upload images or Dicoms. This is part of our TMF but we have no ability to add these to Florence. Also a CTMS would be great. Reasons for choosing Florence eTMF GDPR compliance and ease of use. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. MP Mihaela P. Director, Clinical Research Projects Biotechnology ### "Very good eTMF and document management software" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 February 15, 2023 The Florence team helped with software implementation and deployment, and ensured that the team had adequate training. Pros I love the versatility, and easy of use. Cons I don't really have anything I don't like about the software. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. JL Jing L. Clinical Manager Medical Devices ### "Preliminary use and impression" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 9/10 February 15, 2023 Good! Pros Clean structure, flexibility and useful of functions. Cons eLog can only populate one table. So, could not use for training record where trainer and trainee are two different tables. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. DR Danielle R. Sr. CRS Research ### "Florence eTMF" 4.0 Overall Rating 4.0 4.0 Ease of Use 4.0 4.0 Features 4.0 4.0 Customer Service 0.0 0.0 Likelihood to Recommend 9/10 February 15, 2023 Overall experience is great. Pros Ease of uploading and downloading documents filed. Audit trail is great. Cons Don't like that some documents don't upload and can view within the software and then have to download them separately. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. TT Teri T. CTS Medical Devices ### "Review of the eTMF Florence" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 February 15, 2023 Very pleased with the system and the support. Pros It is easy to move around in this program. Cons I would like for it to stay up longer and not time out. Reasons for choosing Florence eTMF The training for the best I have had in over 18 years. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. MM Maya M. Research Coordinator Research ### "Great tool to use" 4.0 Overall Rating 4.0 4.0 Ease of Use 4.0 4.0 Features 4.0 4.0 Customer Service 0.0 0.0 Likelihood to Recommend 9/10 February 15, 2023 Pros Florence is user friendly and logical. I like that it is easy to edit and upload documents and work as a team. Cons I don't like that there isn't always an easy way to access the website if you don't have the direct link bookmarked on the computer. Review source Incentivized review: software users are invited to submit an honest review and offered a nominal incentive for their time and effort. All incentivized reviews are subject to our verification process prior to publication. [View all Reviews](https://www.capterra.com/p/276610/Florence-eTMF/reviews/) ## Top-rated software of 2026 ### Fill out the form and we'll send a list of the top-rated software based on real user reviews directly to your inbox. Independent research methodology Capterra's researchers use a mix of verified reviews, independent research and objective methodologies to bring you selection and ranking information you can trust. While we may earn a referral fee when you visit a provider through our links or speak to an advisor, this has no influence on our research or methodology. [Learn more](https://www.capterra.com/resources/proprietary-data-research/) How Capterra verifies reviews Capterra carefully verified over 2.5 million+ reviews to bring you authentic software experiences from real users. Our human moderators verify that reviewers are real people and that reviews are authentic. They use leading tech to analyze text quality and to detect plagiarism and generative AI. [Learn more](https://www.capterra.com/resources/how-we-verify-reviews/) How Capterra ensures transparency Capterra lists all providers across its website—not just those that pay us—so that users can make informed purchase decisions. Capterra is free for users. Software providers pay us for sponsored profiles to receive web traffic and sales opportunities. Sponsored profiles include a link-out icon that takes users to the provider's website. [Learn more](https://www.capterra.com/resources/how-we-ensure-transparency/)