# Florence eTMF Reviews 2026. Verified Reviews, Pros & Cons | Capterra > Is Florence eTMF the right Clinical Trial Management solution for you? Explore 18 verified user reviews from people in industries like yours to make a confident choice. Source: https://www.capterra.com/p/276610/Florence-eTMF/reviews --- Florence eTMF 4.6 (18) Provider data verified by our Software Research team, and reviews moderated by our Reviews Verification team. [Learn more](https://www.capterra.com/our-story/) * * * Last updated March 13th, 2026 # Reviews of Florence eTMF Ease of use 4.2 Customer Service 4.8 ## Showing most helpful reviews Showing 1-18 of 18 Reviews Sort by: Most Helpful Rating Company Size Reviewer's Role Length of Use Frequency of Use Sedalia C. Continuous Improvement Quality & Safety Manager Hospital & Health Care Used the software for: 1-2 years ### "Fantastic eTMF!" February 10, 2023 5.0 Pros Florence has incredibly user-friendly software. Cons I would like slightly more control on timeline in the implementation phase. Review Source ME Melissa E. Sr. Manager Clinical Trials Medical Devices Used the software for: 1-2 years ### "Early user's appreciative review" February 13, 2023 5.0 Florence has enables us to go from paper TMF, to electronic TMF- which has been fantastic. We have learned a lot about electronic systems. Pros It has been easy to use Florence, especially once the binders are set up and the roles are established. It has been great for getting signatures from sites, and easily maintaining our TMF and site eISFs. It is so nice to have all the documents in a softare that is easy to navigate, and is constantly improving/ adding new features to make it user friendly. Cons The set up does take time, but there is a learning curve for everything. Especially systems as customizeable as Florence. The delegation of authority log feature has not worked as smoothly as I anticipated, given how many changes to study staff and site PIs that there are. Alternatives considered [Veeva Vault Clinical Operations Suite](https://www.capterra.com/p/254238/Veeva-Vault-Clinical-Operations-Suite/) Reason for choosing Florence eTMF Florence was the most flexible and worked hard to support us through start up and all of our use. Review Source TO Taylor O. Clinical Trial Project Manager Research Used the software for: 1-2 years ### "Great Potential" February 16, 2023 4.0 Pros The email documents to the binder feature is a huge positive. Granting user access it also simple, and the ability to create digital template logs is beneficial. Also, the ability to change the title of a document if there is an error is a huge plus. I've worked in other eTMFs and to change a document name you have to make it "obsolete" and go through tons of other processes to correct it. Cons There is no search function. You cannot search for a specific document if you do not know which folder it is stored in. The binder structure for my studies is complicated, so I sometimes spend 10 minutes trying to decipher where a colleague or site might have saved a specific document. Also, when moving a document, you need to select all the folders to put it in which can be a bit time consuming. Review Source STM Sara Tisj M. Director Clinical Affairs Medical Devices Used the software for: 1-2 years ### "Ease of Use and Compliance " February 15, 2023 4.0 Overall, Florence onboarding and customer service is amazing. They go above and beyond and are always supportive. Although pricing is more than average and there is some downsides overall the experience is great. Pros Florence has the ability to implement a regulatory compliant trial management file system easily for both you and all your clinical sites. Implementing changes within your file structure is easy. Uploading documents and adding users are easy to complete with simple toggles of buttons and drag and drops. Cons Florence still has some challenges in terms of bulk file uploading for example when a new site is onboarded and was previously on paper or transferred. Also, there is no interface to upload images or Dicoms. This is part of our TMF but we have no ability to add these to Florence. Also a CTMS would be great. Reason for choosing Florence eTMF GDPR compliance and ease of use. Review Source VR Verified Reviewer Lead CRA Biotechnology Used the software for: 1-2 years ### "Florence review" February 21, 2023 5.0 paper TMF is a difficult endeavor - this cuts study start in half, and allows for consistent and ongoing visibility into the files so you can keep on top of things. Pros The fact that documents are electronic, easily located and retrievableeasy to share with study sites, easy to collect documents and to QC Cons the reporting features are only worthwhile if everyone including your ISF sites use tags and labels staff training and implementation at the sponsor has been uneven so it is of little value.the search function could use some real updating. lets make it folder specific! Review Source JG Jen G. Clinical Trial Project Manager Research Used the software for: 1-2 years ### "Review" February 10, 2023 4.0 Pros Easy to use, signing and redacting features are wonderful and easy to use. Rarely any questions from sites. Cons We use Florence to create a Delegation of Authorities (DOA) Log and it is so difficult to use. You cannot see all site stafrf's responsibilities (Column with A-Z) activities that gives you ellipses after certain amount of letters and our monitors and team constantly need to download the DOA Log to view staff responsibilities then sort through all site staff versions to come to the most recent one. Would be great for you to make a visually easy to see DOA. Would save our team so much time. Review Source TT Teri T. CTS Medical Devices Used the software for: 1-2 years ### "Review of the eTMF Florence" February 15, 2023 5.0 Very pleased with the system and the support. Pros It is easy to move around in this program. Cons I would like for it to stay up longer and not time out. Reason for choosing Florence eTMF The training for the best I have had in over 18 years. Review Source MP Mihaela P. Director, Clinical Research Projects Biotechnology Used the software for: 2+ years ### "Very good eTMF and document management software" February 15, 2023 5.0 The Florence team helped with software implementation and deployment, and ensured that the team had adequate training. Pros I love the versatility, and easy of use. Cons I don't really have anything I don't like about the software. Review Source MW Miranda W. Lead CRA Research Used the software for: 1-2 years ### "Good Software with Room to Improve" February 10, 2023 4.0 Pros Central document management makes it easy for stakeholders to access and file regulatory documents. Cons The logs are pretty limiting at present and seem to be geared toward tracking information that will not change throughout the trial. It is not conducive for use as a Delegation of Authority log, for example. The Florence team is reportedly working on implementing some of the feedback provided and we look forward to those future changes. Review Source DC Diana C. Sr Staff Clinical Scientist Research Used the software for: 6-12 months ### "Perspective from a Super User" February 10, 2023 5.0 I am essentially still learning how to work Florence but learning every time I use it. The training modules are phenomenal. I am just starting with working with a clinical site which where we have run into some roadblocks with permissions and accessibility. Pros The features I most appreciate in this SW is that fact that we have a centralized location for study files which is critical for our company. The training modules are stellar! Cons What I am having challenges currently is compliance and the allowed roles and responsibilities provided to a clinical site to 'manage' their own ISF. We are having to conduct our own Validation as this has been identified as a gap by our Compliance team. Reason for choosing Florence eTMF I was not involved with the selection process Review Source SG Stephen G. Regulatory Documents Project Manager and IRB Liaison Research Used the software for: 1-2 years ### "Florence eTMF Review\_16FEB2023\_SG" February 16, 2023 5.0 Very satisfied overall. Pros Signature requests are very easy to assign and follow-up on. Cons Moving documents could be easier. Having to drill down through every folder is cumbersome. Review Source TH Tracy H. Project Manager Research Used the software for: 1-2 years ### "Flexible and reporting excellence " February 10, 2023 5.0 Pros The systems flexibility to follow our company processes. Cons A few uploading issues, the system timed out and ended up loading multiple documents. Review Source DR Danielle R. Sr. CRS Research Used the software for: 1-2 years ### "Florence eTMF" February 15, 2023 4.0 Overall experience is great. Pros Ease of uploading and downloading documents filed. Audit trail is great. Cons Don't like that some documents don't upload and can view within the software and then have to download them separately. Review Source LA Leah A. Research Study Monitor Research Used the software for: 1-2 years ### "Florence review" February 10, 2023 5.0 Positive Pros I like the part 11 compliant signature feature the most. Cons I have nothing that I do not like about this software Review Source MM Maya M. Research Coordinator Research Used the software for: 1-2 years ### "Great tool to use" February 15, 2023 4.0 Pros Florence is user friendly and logical. I like that it is easy to edit and upload documents and work as a team. Cons I don't like that there isn't always an easy way to access the website if you don't have the direct link bookmarked on the computer. Review Source SJ Shaminder J. Sr. Clinical Research Associate Medical Devices Used the software for: 6-12 months ### "Florence Review" February 10, 2023 4.0 Pros The ease of use and practicality of importing and exporting documents. Being able to easily locate documents within folders. Cons Folder structure is not consistent within each study which makes it difficult to locate documents if in another folder. Review Source JL Jing L. Clinical Manager Medical Devices Used the software for: Less than 6 months ### "Preliminary use and impression" February 15, 2023 5.0 Good! Pros Clean structure, flexibility and useful of functions. Cons eLog can only populate one table. So, could not use for training record where trainer and trainee are two different tables. Review Source AF Anke F. Clinical Trials Manager Medical Devices Used the software for: Less than 6 months ### "Perscpectinve form a Clinical Trials Manager (Sponsor site) using site's Florence ebinder" February 15, 2023 4.0 It is great to have a shared platform with the site. Pros I like that I have access to the site's reg binder and don't need to bother them about essential documents. I like that they can send me notifications Cons I wished I could set up an alert for myself that emails me whenever a document is uploaded or changed. Review Source