# OpenClinica Software Pricing, Alternatives & More 2026 | Capterra > With the help of Capterra, learn about OpenClinica Software - reviews, pricing plans, popular comparisons to other Electronic Data Capture products and more. Source: https://www.capterra.com/p/78122/OpenClinica --- # OpenClinica Software Review 2026: Features, Integrations, Pros & Cons Last updated on March 13, 2026 Provider data verified by our Software Research team, and reviews moderated by our Reviews Verification team. Independent research methodology Capterra’s researchers use a mix of verified reviews, independent research and objective methodologies to bring you selection and ranking information you can trust. While we may earn a referral fee when you visit a provider through our links or speak to an advisor, this has no influence on our research or methodology. [Learn more](https://www.capterra.com/resources/proprietary-data-research/) How Capterra verifies reviews Capterra carefully verified over 2.5 million+ reviews to bring you authentic software experiences from real users. Our human moderators verify that reviewers are real people and that reviews are authentic. They use leading tech to analyze text quality and to detect plagiarism and generative AI. [Learn more](https://www.capterra.com/resources/how-we-verify-reviews/) How Capterra ensures transparency Capterra lists all providers across its website—not just those that pay us—so that users can make informed purchase decisions. Capterra is free for users. Software providers pay us for sponsored profiles to receive web traffic and sales opportunities. Sponsored profiles include a link-out icon that takes users to the provider’s website. [Learn more](https://www.capterra.com/resources/how-we-ensure-transparency/) [Description](#description)[Use cases](#use-cases)[Alternatives](#alternatives)[Features](#features)[Pricing](#pricing)[Support](#support)[Reviews](#reviews) OpenClinica ## What is OpenClinica? Offering leading biotech and pharmaceutical companies, CROs, academic institutions, and government agencies the foundational clinical data management tools they need (EDC, ePRO/eCOA, RTSM, and reporting) with innovative, next-generation technology (EHR/eSource, RWD, and DCTs) to drive the future of digital clinical trials. ## What is OpenClinica used for? [Electronic Data Capture](https://www.capterra.com/electronic-data-capture-software/)[Clinical Trial Management](https://www.capterra.com/clinical-trial-management-software/)[Data Entry](https://www.capterra.com/data-entry-software/) Top alternative Featured Overall rating Based on 37 user reviews Reviews sentiment Positive 95% Neutral 3% Negative 3% Starting price $1000 Per Month Free trial available Capterra Shortlist charts the highest-rated and most popular products... Our "Best of" badge program showcases products with the highest ratings... Our "Best of" badge program showcases products with the highest ratings... Do you work for OpenClinica?[Manage this product listing](https://digitalmarkets.gartner.com/get-listed/claim-bx?url=http://www.openclinica.com&name=OpenClinica) ## Compare with a popular alternative Capterra selects software alternatives based on relevant features, verified user reviews and user interactions. Placement may be influenced by client status. ### OpenClinica 4.6 (37) VS. [4.9 (21)](https://www.capterra.com/p/133931/ClinCapture/reviews/) Starting Price $1000 Per Month Starting Price $2000 Flat Rate, Per Month Free Trial Free Version Pricing Options Free Trial Free Version Ease Of Use 4.4 (37) Ease Of Use 4.9 (29) Value For Money 4.4 (27) Value For Money 4.8 (21) Customer Service 4.7 (36) Customer Service 4.9 (27) ## OpenClinica alternatives [4.7 (204)](https://www.capterra.com/p/143532/Castor-EDC/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 98% of reviewers rated it above 4 stars Highest Rated [4.9 (66)](https://www.capterra.com/p/126679/RealTime-CTMS/reviews/) Starting price $500.00 Per User, Per Month Pricing Options Free Trial Free Version User Rating 100% of reviewers rated it above 4 stars [Teamscope](https://www.capterra.com/p/179110/Teamscope/) [4.6 (29)](https://www.capterra.com/p/179110/Teamscope/reviews/) Starting price $199.00 Per User, Per Month Pricing Options Free Trial Free Version User Rating 97% of reviewers rated it above 4 stars [Learn More](https://www.capterra.com/p/179110/Teamscope/) [Researchmanager – Clinical Research Suite](https://www.capterra.com/p/192454/Research-Manager/) [4.2 (112)](https://www.capterra.com/p/192454/Research-Manager/reviews/) Starting price Contact vendor for pricing Pricing Options Free Trial Free Version User Rating 86% of reviewers rated it above 4 stars [Learn More](https://www.capterra.com/p/192454/Research-Manager/) [View all alternatives](https://www.capterra.com/p/78122/OpenClinica/alternatives/) ## Features Features with the highest number of reviews are displayed first. Those that have no reviews appear next, sorted alphabetically. Data Capture and Transfer 4.6 (14) 64.29% of 14 reviewers that rated this feature as important or highly important Import, collect, and capture data from multiple sources Data Import/Export 4.1 (14) 50.00% of 14 reviewers that rated this feature as important or highly important Import and export data to and from software applications Audit Trail 4.6 (12) 33.33% of 12 reviewers that rated this feature as important or highly important A record of all activities within the system, including user access, changes made, etc. Clinical Study Management 4.6 (11) 63.64% of 11 reviewers that rated this feature as important or highly important Tools to manage single or multiple clinical studies within a centralized platform Data Verification 4.2 (9) 44.44% of 9 reviewers that rated this feature as important or highly important Process of checking different types of data for accuracy to avoid errors or inconsistencies CRF Tracking 4.7 (7) 28.57% of 7 reviewers that rated this feature as important or highly important Collect and track all case report forms (CRFs) within a centralized repository OpenClinica 35 features Shows that electronic documents are authentic and linked to specific records Dashboard to view the status of ongoing processes, identify current incidents and track past activities Alerts or notifications of various types such as pop-up messages, sounds, banners, or badges Application programming interface that allows for integration with other systems/databases A record of all activities within the system, including user access, changes made, etc. Tools to manage single or multiple clinical studies within a centralized platform Collect and track all case report forms (CRFs) within a centralized repository Customize data fields to support various needs and use cases Customize contracts and forms to collect specific information Import, collect, and capture data from multiple sources Import and export data to and from software applications Process of checking different types of data for accuracy to avoid errors or inconsistencies Graphical representation of data Uses decentralized resources such as network scanners, multi-function devices (MFD), and desktop scanners to collect data and documents Data entry quality control method that involves recording the same data twice to maintain integrity Assemble applications and processes by dragging over and arranging pre-built components Import, collect, and capture data from multiple sources Digitally sign online documents Create and securely store digital patient records Store, manage and track all forms in a centralized location Compliant with HIPAA, which sets standards for sensitive patient data protection Track and manage inventory levels to maintain proper supply Observe and track the demand, usage, progress or quality of a system, product, or user Managing and tracking patient health, progress, communication, and treatment plans Observing and tracking a patient's health status, condition, and wellbeing Randomize the displayed order of questions and answer options Timed notification for any upcoming task, deadline, appointment, or activity Capture data electronically Collection, analysis, and representation of numerical data and generation of reports to understand various patterns View and track pertinent metrics to find patterns and gain insights from data Plan availability and assign specific time slots for tasks and resources Securely stores data to prevent data loss or breaches Manage user accounts, profiles, roles, permissions, and other details across applications, devices or networks Web form that allows users to enter data that is sent and processed for different reasons Create, design and manage workflows for repetitive tasks Features 4.3 (35) 4.3 Based on 35 reviews ## Pricing Value for money 4.4 (27) Free Trial Free Version Basic $1,000 Per Month Value for money 4.4 (27) 4.4 Based on 27 reviews ## Support, customer service and training options Customer Service 4.7 (36) Support - Email/Help Desk - FAQs/Forum - Knowledge Base - Phone Support - 24/7 (Live rep) - Chat Training - In Person - Live Online - Webinars - Documentation - Videos Deployment - Web - Android - iPhone/iPad Typical users - Freelancers - Small businesses - Mid size businesses - Enterprises Customer Service 4.7 (36) 4.7 Based on 36 reviews ## User reviews Overall rating 4.6 Based on 37 reviews Filter by rating 5(28) 4(7) 3(1) 2(0) 1(1) Mentioned topic Sorted by most recent Vanessa G. Head of IT Research ### "OpenClinica for Investigator led Clinical Trials in the UK" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 February 26, 2024 Pros Easy to create and update forms for data collection Cons Automatic scheduling is a bit limited, however this is planned to be updated soon Switched from [Medidata CTMS](https://www.capterra.com/p/84472/Medidata-CTMS/) Alternatives considered [RedCap](https://www.capterra.com/p/234600/RedCap/) [Medidata CTMS](https://www.capterra.com/p/84472/Medidata-CTMS/) Reasons for choosing OpenClinica Overall value, together with compliance and support Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. Adam P. Data Manager Research ### "OC4 for Oncology Clinical Trials" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 4.0 4.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 February 13, 2024 Pros The support provided by the Openclinica team cannot be beat. If I may list two things, the OC system is incredibly user friendly. Cons We needed a centralised system to collect quesitonnaire responses from participants, record that data, enter clinical results, and upload copies of paper work related to each participant visit. This system provides all of the above. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. FL Francesco L. Head of Clinical Data Systems Hospital & Health Care ### "OpenClinica 4" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 8/10 February 12, 2024 Overall the experience with OpenClinica has been very positive so far. Apart from being an all encompassing system, it has a good support infrastructure and works pretty well even with the time zone differences (i.e., US/UK) and usually resolutions are provided in good time. User feedback is always well received and feature changes are genuinely considered to be included in the roadmaps. We have dealt with some pretty complex projects over the last couple of years and have had a positive experience. Pros OpenClinica is a pretty comprehensive platform that can tailor to most if not all needs of data capture. The interface is easy to use and navigate and the drag and drop design features allow even the less technical to be able to create data capture forms with relative ease. There is a lot of material to help users understand the system and the support is good. Cons The customisation of user roles and permission is somewhat restricted meaning there is less flexibility when dealing with multiple different access levels. Some of the additional modules and if professional services have to be engaged to deal with user errors and compliance issues can come up a little on the expensive side especially in a an academic setting. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. KA Kidane A. Clinical Programmer Analyst Biotechnology ### "OpenClinica EDC" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 February 7, 2024 Pros OpenClinica has easy-to-navigate features for users. It is easy to learn. Cons OpenClinica does not replicate blank databases at this time. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. KK Krister K. CTO Information Technology and Services ### "Why I cannot live without OpenClinica" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 February 7, 2024 I have worked with OpenClinica for more than 15 years and loved how it has developed Pros The ease of set up a new study and the management functions Cons I cannot think of anything, have worked with clinical studies my entire professional life and used any tool on the market and OpenClinica has resolved all the issues. Switched from [Oracle Database](https://www.capterra.com/p/5938/Oracle-Database/) Cost and ease of set up including all the tools that has developed since. We started with the open source version Reasons for choosing OpenClinica We had already used the free version of OpenClinica when we decided Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. AB Angelica B. University Intern Pharmaceuticals ### "Enhancing Clinical Trials with OpenClinica: A Comprehensive Review" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 June 26, 2023 I had the chance to collaborate with OpenClinica while I was interning at the university's pharmaceutical product development and research division. The program was essential in organizing the data from research projects and clinical trials. I saw first-hand how OpenClinica's flexible form builder enabled us to precisely develop and collect study-specific data items. The software's user-friendly interface streamlined and expedited the data entering process, decreasing errors and cutting down on data entry time. Our research on the efficacy and safety of medications was supported by OpenClinica's reporting and analytics capabilities, which gave us insights into patient demographics, treatment outcomes, and adverse events. Overall, OpenClinica was a great help in organizing and processing the data we needed for our research activities. Pros For clinical research investigations, OpenClinica has a number of benefits. The program, in the first place, offers a versatile and scalable data management platform that enables researchers to create and collect study-specific data items. The data entry procedure is streamlined, lowering errors and increasing efficiency thanks to its user-friendly interface and intuitive form builder. Researchers can get insightful knowledge from gathered data using OpenClinica's powerful reporting and analytics features, promoting the use of evidence in decision-making. In order to guarantee data integrity and safety, the program also enables regulatory compliance, including data security and audit trails. Overall, OpenClinica equips scientists with a full suite of tools for trustworthy and effective data management in clinical trials and studies. Cons Even though OpenClinica has many advantages, there are a few things to keep in mind. First off, the initial setup and configuration process can be challenging and complicated, necessitating qualified technical knowledge. For non-technical users, the software's advanced functionality could have a longer learning curve, demanding thorough training and continuous assistance. Users have occasionally reported experiencing performance issues with the system, especially when working with huge datasets or intricate study designs. Additionally, for smaller research institutions with tighter budgets, the cost structure of the program can be a barrier. Despite these factors, OpenClinica is a smart choice for clinical research studies due to its flexibility, extensive data management capabilities, and compliance features. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. DP Dmitriy P. Clinical Data Programmer Research ### "OpenClinica 4" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 9/10 December 20, 2022 Great improvement of the form builder in the new version. Had excellent customer service with the IT department. Pros Form designer has been helpful. Great customer support. Cons so far the software had everything that I needed. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. NP Nick P. Research Associate Research ### "A useful tool in a multicentre clinical trial" 4.0 Overall Rating 4.0 4.0 Ease of Use 4.0 4.0 Features 4.0 4.0 Customer Service 5.0 5.0 Likelihood to Recommend 7/10 December 12, 2022 Pros The ability to structure events and related forms which can be assigned to research staff or completed by participants electronically. The software is easy to use for data collection which is hugely important which many staff spread over many centres need to use it effectively. Cons I would prefer data extraction to be more customisable/targeted. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. JT Judy T. Director of Operations Research ### "OpenClinica Software Setup" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 4.0 4.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 December 1, 2022 OpenClinica is a great software program. If you have someone who can dedicate the time to program it, then you can get it exactly how you want it. We used the excel sheets to program ours and not the other way. I'm sure it is easier to do it the other way, but it didn't have the additional feature like we wanted without using the excel sheets. Overall it is an excellent product and one I would recommend. Pros The training was really nice and their support line is fast. They have a 24 hour turn around and sometimes they are much faster than that. It was easy to program once I learned how to do it. We did like the example files, like the Kitchen Sink file. Most everything we needed could be found there. Cons It was a bit of a learning curve to get how to use this software but I must admit, once we learned how to use it, it wasn't bad. There are some sorting features with long drug lists that are tough to use at times. Drop down features are a bit rough but once we figured it out, it wasn't too bad.We would have liked training videos for the excel sheets if you didn't remember your superuser training functions. Reasons for choosing OpenClinica Superuser training was a plus and it was the best value for the price. Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. MP Malgorzata P. CDM Pharmaceuticals ### "Very easy to use, user friendly and logic system" 5.0 Overall Rating 5.0 5.0 Ease of Use 5.0 5.0 Features 5.0 5.0 Customer Service 5.0 5.0 Likelihood to Recommend 10/10 November 17, 2022 I really like the system - you do not have to know much about programming to use it and the OC support is just amazing Pros OpenClinica is a system which is very easy to use - for the basic use you can simply start with the designer and create EDC. The system is not overloaded with information and therefore user-friendly. I use this program every day in my projects and my clients also praise this system very much - after a short training they are able to start using it. I really appreciate that the system allows for many possibilities to design CRFs. A super useful thing are also the ePROs and ruls option. Cons I hope new guideline version will be more detailed - the one which is available is very general Review source Non-incentivized review: any software user can leave a review for any product listed on our site. All submitted reviews are subject to our verification process prior to publication. Response from Vendor November 28, 2022 Thank you for the wonderful review, Malgorzata. We continue to work on the OpenClinica Documentation and Training site to add greater detail and organization. [View all Reviews](https://www.capterra.com/p/78122/OpenClinica/reviews/) ## Top-rated software of 2026 ### Fill out the form and we'll send a list of the top-rated software based on real user reviews directly to your inbox. Independent research methodology Capterra's researchers use a mix of verified reviews, independent research and objective methodologies to bring you selection and ranking information you can trust. While we may earn a referral fee when you visit a provider through our links or speak to an advisor, this has no influence on our research or methodology. [Learn more](https://www.capterra.com/resources/proprietary-data-research/) How Capterra verifies reviews Capterra carefully verified over 2.5 million+ reviews to bring you authentic software experiences from real users. Our human moderators verify that reviewers are real people and that reviews are authentic. They use leading tech to analyze text quality and to detect plagiarism and generative AI. [Learn more](https://www.capterra.com/resources/how-we-verify-reviews/) How Capterra ensures transparency Capterra lists all providers across its website—not just those that pay us—so that users can make informed purchase decisions. Capterra is free for users. Software providers pay us for sponsored profiles to receive web traffic and sales opportunities. Sponsored profiles include a link-out icon that takes users to the provider's website. [Learn more](https://www.capterra.com/resources/how-we-ensure-transparency/)