# Page 2 | OpenClinica Reviews 2026. Verified Reviews, Pros & Cons | Capterra

> Page 2 - Is OpenClinica the right Electronic Data Capture solution for you? Explore 37 verified user reviews from people in industries like yours to make a confident choice.

Source: https://www.capterra.com/p/78122/OpenClinica/reviews

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OpenClinica

4.6 (37)

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Last updated March 13th, 2026

# Page 2 - Reviews of OpenClinica

## Showing most helpful reviews

Showing 26-37 of 37 Reviews

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Most Helpful

Rating

Company Size

Reviewer's Role

Length of Use

Frequency of Use

DM

David M.  
Senior Trials Programmer  
Research  
Used the software for: 2+ years

### "OpenClinica 4 makes setting up new studies a breeze"

October 1, 2020

5.0

I have been using OpenClinica for nine years, the majority of which I have used OC3, which performed well (and still does) but was lacking features other alternative products offered. However, since the release of OC4 that has all changed. OC4 is a exceptional product and a significant improvement from OC3. The ease of use has saved countless working hours but also produces high quality eCRFs - a product the OpenClinica team should be immensely proud of.

Pros

OC4 is extremely user friendly for both administrators and users. The study build is straight forward, allowing for powerful eCRFs to be designed, developed and validated with ease. Excellent customer support.

Cons

Some more search functionality when trying to find users and sites. Ability to archive studies.

Review Source

Response from OpenClinica

October 14, 2020

Thank you for your review David. It's wonderful to hear how you have embraced OC4 and recognize the work that the team has done in optimizing the experience for our users. Your improvement suggestions are much appreciated as well.

RV

Roberto V.  
CIO  
Hospital & Health Care  
Used the software for: 2+ years

### "Excellent Product"

February 11, 2022

5.0

Pros

This product has many positive features, especially mobile crf management. It has a very good audit trail. It is easy to use. The customer support is very efficient.

Cons

The software does not natively manage GDPR privacy, and it would be useful to have more flexibility and autonomous management of randomization lists

Review Source

PM

Patrick M.  
Senior Director of Data Management  
Research  
Used the software for: 2+ years

### "Great product, stable for many years, always incorporating new features, great support, open source"

August 23, 2017

5.0

Solid platform, great user support, query system, design is currently spreadsheet based which appeals to the minds of programmers, lots of options for data export, have used it in multi-country clinical and observational trials.

Pros

Great interface for sites to enter data for their subjects, repeating rows for AEs and con meds, validated system, automatic data exports, robust querying system, dynamic display of questions on one form based on answers from another form, great visual cues for data entry staff (colors, icons are meaningful), calendar control is powerful and easy to write data cleaning checks for, version control of forms, strong data integrity (can't change pre-programmed answer sets for questions without adequate control), great user support including option to contract for development at reasonable prices, built-in support for double data entry of paper forms, stable over the 7 years I've used it for clinical and observational trials, incredible user community which makes 3rd party tools available, yearly international conferences to keep users up to date, patient PRO module is very feature laden, patient PRO module creates solid link between site CRF data and patient PRO data, I have used it for 7 years and have never lost a data point.

Cons

Would like to have patient compensation built-in to patient PRO module, more reports needed but are coming based on user feedback.

Review Source

NP

Nick P.  
Research Associate  
Research  
Used the software for: 2+ years

### "A useful tool in a multicentre clinical trial"

December 12, 2022

4.0

Pros

The ability to structure events and related forms which can be assigned to research staff or completed by participants electronically. The software is easy to use for data collection which is hugely important which many staff spread over many centres need to use it effectively.

Cons

I would prefer data extraction to be more customisable/targeted.

Review Source

CC

Cathy C.  
Clinical data programmer  
Non-Profit Organization Management  
Used the software for: 1-2 years

### "Great EDC platform"

November 8, 2022

5.0

Pros

It is intuitive and ease of use. Also I like Metabase which is easy to query data by using SQL.

Cons

Overall, my experience has been well with OPenClinica.

Review Source

Response from OpenClinica

November 11, 2022

Thank you for your review, Cathy. We are delighted that you find it intuitive and easy to use. Insight is an integral part of the platform and I'm impressed that you are building your own SQL queries. I myself enjoy the easy report and dashboard building capabilities so I'm humbled by folks that use the more advanced features.

VA

VICENTE A.  
INTERNATIONAL DIRECTOR  
Research  
Used the software for: 2+ years

### "OpenClinica makes it simple. Flexible, reliable and easy to use"

November 21, 2017

5.0

Flexible, reliable and easy to use

Pros

I have had a great experience using OpenClinica EDC during the last 3 years with several studies (Observational studies, Registries and Clinical Trials). It´s a web based solution to build and manage multi-sites clinical studies. It´s a powerful platform, great user support, Data Entry and DM capabilities makes everything simple. The study build and CRF designer allows re-use across studies. Updates and amendments are a simple process. Audit trail is excellent and easy to track and data extractions are available in several formats whenever is needed for the statistician. Data management capabilities improves data quality and productive monitoring. Most CRAs were pleased with the system. OpenClinica offers Cloud Services. No need IT skills for installation and setup. Super User Training is very helpful for data managers when building CRFs. If regulatory submission is required, the Regulatory Support Package service is highly recommended.

Cons

Programmer skills are needed to implement complex validations during CRF design. Complex reports should be customized in Excel after data extract.

Review Source

PC

Phillip C.  
Data Systems Programmer  
Computer Software  
Used the software for: 2+ years

### "Best in Class"

November 3, 2022

5.0

Pros

Easy development.Easy troubleshooting.Easy query management.

Cons

Only one query allowed per field.Dynamic fields don't update unless form reopened.

Review Source

MP

Maya P.  
Clinical Project Manager  
Research  
Used the software for: 2+ years

### "OpenClinica Use"

February 2, 2022

5.0

Overall I have been very happy with the use of this system. I have trained Clinical Sites to use OpenClinica and the help desk is very good at answering my questions.

Pros

Ease of use once you have been trained on the software

Cons

I wish it would be integrated to a Finance system as well as a Clinical Trial Management System.

Review Source

Response from OpenClinica

February 3, 2022

Thank you for your review Maya! We appreciate your feedback. With our set of RESTful APIs, folks have been quite successful in integrating with CTM systems which are primarily for project, site management, site and patient payments, etc. where EDC (CDMS) is really the source for the clinical trial data. Thank you again!

VR

Verified Reviewer  
Manager, Clinical Data Management  
  
Used the software for: Less than 6 months

### "I've been using OC3 for 10 years, transitioning to OC4 has been painless. The knowledge transfers."

April 10, 2018

5.0

Pros

OpenClinica has listened to their customers and it shows with this new product. Being a user for 10 years, I see the features I have personally requested in OC3 appear in OC4. The people behind the product have passion for their product.

Cons

I have trouble with using it on different internet browsers. Seems to be optimize, in my experience, for Firefox.

Review Source

DP

Dmitriy P.  
Clinical Data Programmer  
Research  
Used the software for: Less than 6 months

### "OpenClinica 4"

December 20, 2022

5.0

Great improvement of the form builder in the new version. Had excellent customer service with the IT department.

Pros

Form designer has been helpful. Great customer support.

Cons

so far the software had everything that I needed.

Review Source

EO

Evance O.  
Data Manager  
  
Used the software for:

### "I have used OC to successfully manage more than 5 clinical trial studies."

July 10, 2015

4.0

Compatibility with browsers other than IE is a major problem. In-Flexibility in changing CRF versions.

Review Source

AK

Ahmed K.  
System administrator  
  
Used the software for:

### "Great system"

March 2, 2015

5.0

all free functions are great with good security as a web application and acceptable free suport.

Review Source

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